An Adenovirus Type 5 (Ad5) Amplicon-Based Packaging Cell Line for Production of High-Capacity Helper-Independent ΔE1-E2-E3-E4 Ad5 Vectors

Production of multiply deleted adenoviral (Ad) vectors with increased cloning capacity and reduced immunogenicity to adenovirus gene products requires the concomitant generation of efficient packaging cell lines. High expression levels of the complementing genes must be achieved in a coordinated fas...

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Bibliographische Detailangaben
Hauptverfasser: Catalucci, Daniele, Sporeno, Elisabetta, Cirillo, Agostino, Ciliberto, Gennaro, Nicosia, Alfredo, Colloca, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Gene Delivery
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091673/
https://ncbi.nlm.nih.gov/pubmed/15858023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6400-6409.2005
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