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An Adenovirus Type 5 (Ad5) Amplicon-Based Packaging Cell Line for Production of High-Capacity Helper-Independent ΔE1-E2-E3-E4 Ad5 Vectors

Production of multiply deleted adenoviral (Ad) vectors with increased cloning capacity and reduced immunogenicity to adenovirus gene products requires the concomitant generation of efficient packaging cell lines. High expression levels of the complementing genes must be achieved in a coordinated fas...

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Bibliografiske detaljer
Main Authors: Catalucci, Daniele, Sporeno, Elisabetta, Cirillo, Agostino, Ciliberto, Gennaro, Nicosia, Alfredo, Colloca, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1091673/
https://ncbi.nlm.nih.gov/pubmed/15858023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.10.6400-6409.2005
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