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Point Mutations in the WD40 Domain of Eed Block Its Interaction with Ezh2

The Polycomb group proteins are involved in maintenance of the silenced state of several developmentally regulated genes. These proteins form large aggregates with different subunit compositions. To explore the nature of these complexes and their function, we used the full-length Eed (embryonic ecto...

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Autors principals: Denisenko, Oleg, Shnyreva, Maria, Suzuki, Hideaki, Bomsztyk, Karol
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109149/
https://ncbi.nlm.nih.gov/pubmed/9742080
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