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Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant

mRNA in the yeast Saccharomyces cerevisiae is primarily degraded through a pathway that is stimulated by removal of the mRNA cap structure. Here we report that a mutation in the SPB8 (YJL124c) gene, initially identified as a suppressor mutation of a poly(A)-binding protein (PAB1) gene deletion, stab...

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Pubblicato in:Mol Cell Biol
Autori principali: Boeck, Ronald, Lapeyre, Bruno, Brown, Christine E., Sachs, Alan B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9710590/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.9.5062
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