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Functional Analysis of Coordinated Cleavage in V(D)J Recombination

V(D)J recombination in vivo requires a pair of signals with distinct spacer elements of 12 and 23 bp that separate conserved heptamer and nonamer motifs. Cleavage in vitro by the RAG1 and RAG2 proteins can occur at individual signals when the reaction buffer contains Mn(2+), but cleavage is restrict...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Kim, Deok Ryong, Oettinger, Marjorie A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109054/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.8.4679
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