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Effect of nebulised recombinant DNase on neutrophil elastase load in cystic fibrosis.

BACKGROUND: DNA released by degenerating inflammatory neutrophils contributes to mucous plugging of airways in patients with cystic fibrosis. Neutrophil elastase, a major effector of tissue destruction in the lungs of patients with cystic fibrosis, is a highly cationic molecule which is bound and in...

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Detalhes bibliográficos
Main Authors: Costello, C M, O'Connor, C M, Finlay, G A, Shiels, P, FitzGerald, M X, Hayes, J P
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1090494/
https://ncbi.nlm.nih.gov/pubmed/8693445
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