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Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis

Joint ankylosis is a major cause of disability in the human spondyloarthropathies. Here we report that this process partially recapitulates embryonic endochondral bone formation in a spontaneous model of arthritis in DBA/1 mice. Bone morphogenetic protein (BMP) signaling appears to be a key molecula...

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Bibliografische gegevens
Hoofdauteurs: Lories, Rik J.U., Derese, Inge, Luyten, Frank P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1090472/
https://ncbi.nlm.nih.gov/pubmed/15902307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23738
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