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Modulation of bone morphogenetic protein signaling inhibits the onset and progression of ankylosing enthesitis
Joint ankylosis is a major cause of disability in the human spondyloarthropathies. Here we report that this process partially recapitulates embryonic endochondral bone formation in a spontaneous model of arthritis in DBA/1 mice. Bone morphogenetic protein (BMP) signaling appears to be a key molecula...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1090472/ https://ncbi.nlm.nih.gov/pubmed/15902307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23738 |
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