Binding of Shp2 Tyrosine Phosphatase to FRS2 Is Essential for Fibroblast Growth Factor-Induced PC12 Cell Differentiation

Eitemau Tebyg

• FRS2 Proteins Recruit Intracellular Signaling Pathways by Binding to Diverse Targets on Fibroblast Growth Factor and Nerve Growth Factor Receptors
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  Cyhoeddwyd: (2000)
• Critical role for the docking-protein FRS2α in FGF receptor-mediated signal transduction pathways
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  Cyhoeddwyd: (2001)
• A role for the SHP-2 tyrosine phosphatase in nerve growth-induced PC12 cell differentiation.
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• Docking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade
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  Cyhoeddwyd: (2001)
• Tyrosine phosphorylation sites on FRS2α responsible for Shp2 recruitment are critical for induction of lens and retina
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  Cyhoeddwyd: (2004)