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Schistosome Satellite DNA Encodes Active Hammerhead Ribozymes

Using a computer program designed to search for RNA structural motifs in sequence databases, we have found a hammerhead ribozyme domain encoded in the Smα repetitive DNA of Schistosoma mansoni. Transcripts of these repeats are expressed as long multimeric precursor RNAs that cleave in vitro and in v...

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Bibliografiske detaljer
Main Authors: Ferbeyre, Gerardo, Smith, James M., Cedergren, Robert
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108972/
https://ncbi.nlm.nih.gov/pubmed/9632772
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