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No Requirement for V(D)J Recombination in p53-Deficient Thymic Lymphoma

The p53 tumor suppressor is activated in response to a variety of cellular stress signals, although specific in vivo signals that trigger tumor suppression are unknown. In mouse thymocytes, where p53 inactivation leads to tumorigenesis, several observations suggest that V(D)J recombination of T-cell...

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Detalhes bibliográficos
Main Authors: Liao, Mai-Jing, Zhang, Xiao-Xiang, Hill, Rosina, Gao, Jingjin, Qumsiyeh, Mazin B., Nichols, Warren, Van Dyke, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC108930/
https://ncbi.nlm.nih.gov/pubmed/9584189
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