GATA-4 and Nkx-2.5 Coactivate Nkx-2 DNA Binding Targets: Role for Regulating Early Cardiac Gene Expression

The cardiogenic homeodomain factor Nkx-2.5 and serum response factor (SRF) provide strong transcriptional coactivation of the cardiac α-actin (αCA) promoter in fibroblasts (C. Y. Chen and R. J. Schwartz, Mol. Cell. Biol. 16:6372–6384, 1996). We demonstrate here that Nkx-2.5 also cooperates with GATA...

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में प्रकाशित:	Mol Cell Biol
मुख्य लेखकों:	Sepulveda, Jorge L., Belaguli, Narashimaswamy, Nigam, Vishal, Chen, Ching-Yi, Nemer, Mona, Schwartz, Robert J.
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Taylor & Francis 1998
विषय:	Transcriptional Regulation
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108922/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9584181/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.6.3405
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