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GATA-4 and Nkx-2.5 Coactivate Nkx-2 DNA Binding Targets: Role for Regulating Early Cardiac Gene Expression

The cardiogenic homeodomain factor Nkx-2.5 and serum response factor (SRF) provide strong transcriptional coactivation of the cardiac α-actin (αCA) promoter in fibroblasts (C. Y. Chen and R. J. Schwartz, Mol. Cell. Biol. 16:6372–6384, 1996). We demonstrate here that Nkx-2.5 also cooperates with GATA...

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Détails bibliographiques
Auteurs principaux: Sepulveda, Jorge L., Belaguli, Narashimaswamy, Nigam, Vishal, Chen, Ching-Yi, Nemer, Mona, Schwartz, Robert J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC108922/
https://ncbi.nlm.nih.gov/pubmed/9584181
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