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Flexible Positioning of the Telomerase-Associated Nuclease Leads to Preferential Elimination of Nontelomeric DNA

In addition to a reverse transcriptase activity, telomerase is associated with a DNA endonuclease that removes nucleotides from a primer 3′ terminus prior to telomere repeat addition. Here we examine the DNA specificity of the primer cleavage-elongation reaction carried out by the Euplotes crassus t...

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Auteurs principaux: Greene, Eric C., Bednenko, Janna, Shippen, Dorothy E.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC108869/
https://ncbi.nlm.nih.gov/pubmed/9488471
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