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Initiator-Elongator Discrimination in Vertebrate tRNAs for Protein Synthesis

Initiator tRNAs are used exclusively for initiation of protein synthesis and not for the elongation step. We show, in vivo and in vitro, that the primary sequence feature that prevents the human initiator tRNA from acting in the elongation step is the nature of base pairs 50:64 and 51:63 in the TΨC...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Drabkin, Harold J., Estrella, Melanie, Rajbhandary, Uttam L.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1998
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108860/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488462/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1459
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