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The Nuclear Corepressors NCoR and SMRT Are Key Regulators of Both Ligand- and 8-Bromo-Cyclic AMP-Dependent Transcriptional Activity of the Human Progesterone Receptor

Previously, we defined a novel class of ligands for the human progesterone receptor (PR) which function as mixed agonists. These compounds induce a conformational change upon binding the receptor that is different from those induced by agonists and antagonists. This establishes a correlation between...

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Udgivet i:Mol Cell Biol
Principais autores: Wagner, Brandee L., Norris, John D., Knotts, Trina A., Weigel, Nancy L., McDonnell, Donald P.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108850/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488452/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1369
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