Distinct role of lymphocyte function-associated antigen-1 in mediating effective cytolytic activity by cytotoxic T lymphocytes

Lymphocyte function-associated antigen-1 (LFA-1) interaction with intercellular adhesion molecules (ICAMs) facilitates T cell antigen receptor (TCR)-mediated killing. To dissect TCR and LFA-1 contributions, we evaluated cytolytic activity and granule release by cytotoxic T lymphocytes (CTL) as well...

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Main Authors: Anikeeva, Nadia, Somersalo, Kristina, Sims, Tasha N., Thomas, V. Kaye, Dustin, Michael L., Sykulev, Yuri
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088394/
https://ncbi.nlm.nih.gov/pubmed/15851656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502467102
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