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Mas Oncogene Signaling and Transformation Require the Small GTP-Binding Protein Rac

The Mas oncogene encodes a novel G-protein-coupled receptor that was identified originally as a transforming protein when overexpressed in NIH 3T3 cells. The mechanism and signaling pathways that mediate Mas transformation have not been determined. We observed that the foci of transformed NIH 3T3 ce...

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Main Authors: Zohn, Irene E., Symons, Marc, Chrzanowska-Wodnicka, Magdalena, Westwick, John K., Der, Channing J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC108835/
https://ncbi.nlm.nih.gov/pubmed/9488437
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