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Distinct Domains of IκBα Regulate c-Rel in the Cytoplasm and in the Nucleus

IκBα is a critical regulator of Rel/NF-κB-mediated gene activation. It controls the induction of NF-κB factors by retaining them in the cytoplasm and also functions in the nucleus to terminate the induction process. In this study, we show that IκBα regulates the transcriptional activity of c-Rel in...

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Autors principals: Luque, Ignacio, Gélinas, Céline
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC108834/
https://ncbi.nlm.nih.gov/pubmed/9488436
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