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Oxygenation Inhibits the Physiological Tissue-Protecting Mechanism and Thereby Exacerbates Acute Inflammatory Lung Injury

Acute respiratory distress syndrome (ARDS) usually requires symptomatic supportive therapy by intubation and mechanical ventilation with the supplemental use of high oxygen concentrations. Although oxygen therapy represents a life-saving measure, the recent discovery of a critical tissue-protecting...

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Detalhes bibliográficos
Main Authors: Thiel, Manfred, Chouker, Alexander, Ohta, Akio, Jackson, Edward, Caldwell, Charles, Smith, Patrick, Lukashev, Dmitry, Bittmann, Iris, Sitkovsky, Michail V
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1088279/
https://ncbi.nlm.nih.gov/pubmed/15857155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0030174
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