Activity of a Trypanosome Metacyclic Variant Surface Glycoprotein Gene Promoter Is Dependent upon Life Cycle Stage and Chromosomal Context

African trypanosomes evade the mammalian host immune response by antigenic variation, the continual switching of their variant surface glycoprotein (VSG) coat. VSG is first expressed at the metacyclic stage in the tsetse fly as a preadaptation to life in the mammalian bloodstream. In the metacyclic...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Graham, Sheila V., Wymer, Ben, Barry, J. David
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108826/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9488428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.3.1137
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