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Activity of a Trypanosome Metacyclic Variant Surface Glycoprotein Gene Promoter Is Dependent upon Life Cycle Stage and Chromosomal Context

African trypanosomes evade the mammalian host immune response by antigenic variation, the continual switching of their variant surface glycoprotein (VSG) coat. VSG is first expressed at the metacyclic stage in the tsetse fly as a preadaptation to life in the mammalian bloodstream. In the metacyclic...

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Main Authors: Graham, Sheila V., Wymer, Ben, Barry, J. David
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC108826/
https://ncbi.nlm.nih.gov/pubmed/9488428
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