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Characterization of the p53-Dependent Postmitotic Checkpoint following Spindle Disruption
The p53 tumor suppressor gene product is known to act as part of a cell cycle checkpoint in G(1) following DNA damage. In order to investigate a proposed novel role for p53 as a checkpoint at mitosis following disruption of the mitotic spindle, we have used time-lapse videomicroscopy to show that bo...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
1998
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC108818/ https://ncbi.nlm.nih.gov/pubmed/9448003 |
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