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Hepatitis B Virus X-Associated Protein 2 Is a Subunit of the Unliganded Aryl Hydrocarbon Receptor Core Complex and Exhibits Transcriptional Enhancer Activity

Prior to ligand activation, the unactivated aryl hydrocarbon receptor (AhR) exists in a heterotetrameric 9S core complex consisting of the AhR ligand-binding subunit, a dimer of hsp90, and an unknown subunit. Here we report the purification of an ∼38-kDa protein (p38) from COS-1 cell cytosol that is...

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Publicat a:Mol Cell Biol
Autors principals: Meyer, Brian K., Pray-Grant, Marilyn G., Vanden Heuvel, John P., Perdew, Gary H.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1998
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108810/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9447995/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.2.978
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