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The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90

The aryl hydrocarbon receptor is a member of the nuclear receptor superfamily that associates with the molecular chaperone HSP90 in the cytoplasm. The activation mechanism of the AhR is not yet fully understood. It has been proposed that after binding of ligands such as 2,3,7,8-tetrachlorodibenzo-p-...

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Principais autores: Noriko Tsuji, Kana Fukuda, Yuhtaroh Nagata, Hirotaka Okada, Asami Haga, Shiori Hatakeyama, Shiho Yoshida, Tomoya Okamoto, Miki Hosaka, Kazuhiro Sekine, Kei Ohtaka, Soh Yamamoto, Michiro Otaka, Ewa Grave, Hideaki Itoh
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2014-01-01
coleção:FEBS Open Bio
Assuntos:
Aryl hydrocarbon receptor
AhR
Dioxin receptor
Molecular chaperone
HSP90
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211546314000850
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