The AML1-MTG8 Leukemic Fusion Protein Forms a Complex with a Novel Member of the MTG8(ETO/CDR) Family, MTGR1

The AML1-CBFβ transcription factor complex is essential for the definitive hematopoiesis of all lineages and is the most frequent target of chromosomal rearrangements in human leukemia. In the t(8;21) translocation associated with acute myeloid leukemia (AML), the AML1(CBFA2/PEBP2αB) gene is juxtapo...

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Bibliographische Detailangaben
Hauptverfasser: Kitabayashi, Issay, Ida, Kohmei, Morohoshi, Fumiko, Yokoyama, Akihiko, Mitsuhashi, Naoko, Shimizu, Kimiko, Nomura, Nobuo, Hayashi, Yasuhide, Ohki, Misao
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC108796/
https://ncbi.nlm.nih.gov/pubmed/9447981
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