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A method for the prediction of GPCRs coupling specificity to G-proteins using refined profile Hidden Markov Models
BACKGROUND: G- Protein coupled receptors (GPCRs) comprise the largest group of eukaryotic cell surface receptors with great pharmacological interest. A broad range of native ligands interact and activate GPCRs, leading to signal transduction within cells. Most of these responses are mediated through...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087828/ https://ncbi.nlm.nih.gov/pubmed/15847681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-6-104 |
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