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Restoration of Functional Gap Junctions through Internal Ribosome Entry Site-Dependent Synthesis of Endogenous Connexins in Density-Inhibited Cancer Cells

Gap junctions are composed of connexins and are critical for the maintenance of the differentiated state. Consistently, connexin expression is impaired in most cancer cells, and forced expression of connexins following cDNA transfection reverses the tumor phenotype. We have found that the restoratio...

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Bibliografische gegevens
Hoofdauteurs: Lahlou, Hicham, Fanjul, Marjorie, Pradayrol, Lucien, Susini, Christiane, Pyronnet, Stéphane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087721/
https://ncbi.nlm.nih.gov/pubmed/15870276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.10.4034-4045.2005
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