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Structural Requirements for Glycosaminoglycan Recognition by the Lyme Disease Spirochete, Borrelia burgdorferi

Borrelia burgdorferi, the Lyme disease agent, binds glycosaminoglycans (GAGs) such as heparin, heparan sulfate, and dermatan sulfate. Heparin or heparan sulfate fractions separated by size or charge were tested for their ability to inhibit attachment of B. burgdorferi to Vero cells. GAG chains of in...

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Main Authors: Leong, John M., Robbins, Douglas, Rosenfeld, Louis, Lahiri, Biswajit, Parveen, Nikhat
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC108771/
https://ncbi.nlm.nih.gov/pubmed/9826395
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