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Structural Requirements for Glycosaminoglycan Recognition by the Lyme Disease Spirochete, Borrelia burgdorferi

Borrelia burgdorferi, the Lyme disease agent, binds glycosaminoglycans (GAGs) such as heparin, heparan sulfate, and dermatan sulfate. Heparin or heparan sulfate fractions separated by size or charge were tested for their ability to inhibit attachment of B. burgdorferi to Vero cells. GAG chains of in...

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Udgivet i:Infect Immun
Principais autores: Leong, John M., Robbins, Douglas, Rosenfeld, Louis, Lahiri, Biswajit, Parveen, Nikhat
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1998
Fag:
Molecular and Cellular Pathogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826395/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.12.6045-6048.1998
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