Contrasting Roles of Mannan-Specific Monoclonal Immunoglobulin M Antibodies in the Activation of Classical and Alternative Pathways by Candida albicans

Polyclonal antimannan immunoglobulin G (IgG) activates the classical complement pathway and accelerates initiation of the alternative pathway by Canidida albicans. This dual role was assessed for two antimannan IgM monoclonal antibodies (MAbs). MAb B6.1 is specific for an epitope on the acid-labile...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Zhang, Mason X., Cutler, Jim E., Han, Yongmoon, Kozel, Thomas R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Host Response and Inflammation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108767/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826391/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.12.6027-6029.1998
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