Contrasting Roles of Mannan-Specific Monoclonal Immunoglobulin M Antibodies in the Activation of Classical and Alternative Pathways by Candida albicans

Polyclonal antimannan immunoglobulin G (IgG) activates the classical complement pathway and accelerates initiation of the alternative pathway by Canidida albicans. This dual role was assessed for two antimannan IgM monoclonal antibodies (MAbs). MAb B6.1 is specific for an epitope on the acid-labile...

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Hlavní autoři: Zhang, Mason X., Cutler, Jim E., Han, Yongmoon, Kozel, Thomas R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC108767/
https://ncbi.nlm.nih.gov/pubmed/9826391
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