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Pharmacodynamic Activity of Telithromycin at Simulated Clinically Achievable Free-Drug Concentrations in Serum and Epithelial Lining Fluid against Efflux (mefE)-Producing Macrolide- Resistant Streptococcus pneumoniae for Which Telithromycin MICs Vary

The present study, using an in vitro model, assessed telithromycin pharmacodynamic activity at simulated clinically achievable free-drug concentrations in serum (S) and epithelial lining fluid (ELF) against efflux (mefE)-producing macrolide-resistant Streptococcus pneumoniae. Two macrolide-susceptib...

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Main Authors: Zhanel, George G., Johanson, Christel, Laing, Nancy, Hisanaga, Tamiko, Wierzbowski, Aleksandra, Hoban, Daryl J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087669/
https://ncbi.nlm.nih.gov/pubmed/15855517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1943-1948.2005
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