Pharmacodynamic Modeling of Clarithromycin against Macrolide-Resistant [PCR-Positive mef(A) or erm(B)] Streptococcus pneumoniae Simulating Clinically Achievable Serum and Epithelial Lining Fluid Free-Drug Concentrations

Eitemau Tebyg

• Macrolide-Resistant Streptococcus pneumoniae in Canada during 1998–1999: Prevalence of mef(A) and erm(B) and Susceptibilities to Ketolides
  gan: Hoban, Daryl J., et al.
  Cyhoeddwyd: (2001)
• Pharmacodynamic Activity of Telithromycin at Simulated Clinically Achievable Free-Drug Concentrations in Serum and Epithelial Lining Fluid against Efflux (mefE)-Producing Macrolide- Resistant Streptococcus pneumoniae for Which Telithromycin MICs Vary
  gan: Zhanel, George G., et al.
  Cyhoeddwyd: (2005)
• Expression of the mef(E) Gene Encoding the Macrolide Efflux Pump Protein Increases in Streptococcus pneumoniae with Increasing Resistance to Macrolides
  gan: Wierzbowski, Aleksandra K., et al.
  Cyhoeddwyd: (2005)
• Molecular Epidemiology and Prevalence of Macrolide Efflux Genes mef(A) and mef(E) in Streptococcus pneumoniae Obtained in Canada from 1997 to 2002
  gan: Wierzbowski, Aleksandra K., et al.
  Cyhoeddwyd: (2005)
• Antimicrobial Susceptibility and Macrolide Resistance Inducibility of Streptococcus pneumoniae Carrying erm(A), erm(B), or mef(A)
  gan: Syrogiannopoulos, George A., et al.
  Cyhoeddwyd: (2003)