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Pharmacokinetics of Tenofovir in Breast Milk of Lactating Rhesus Macaques

To study tenofovir transfer into milk, two lactating macaques were given a subcutaneous dose of tenofovir (30 mg/kg of body weight). Peak concentrations and area under the curve values of tenofovir in milk were ∼3 and ∼20% of those detected in serum, respectively.

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Bibliographische Detailangaben
Hauptverfasser: Van Rompay, Koen K. A., Hamilton, Marta, Kearney, Brian, Bischofberger, Norbert
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087653/
https://ncbi.nlm.nih.gov/pubmed/15855535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.2093-2094.2005
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