Clinical Pharmacokinetics of Alamifovir and Its Metabolites

Alamifovir, a purine nucleotide analogue prodrug, and its hydrolyzed derivatives have shown preclincal efficacy activity against wild-type and lamivudine-resistant hepatitis B virus. Two studies were conducted to examine the single- and multiple-dose alamifovir pharmacokinetics after oral administra...

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Detalhes bibliográficos
Main Authors: Chan, Clark, Abu-Raddad, Eyas, Golor, Georg, Watanabe, Hikari, Sasaki, Akira, Yeo, Kwee Poo, Soon, Danny, Sinha, Vikram P., Flanagan, Shawn D., He, Minxia M., Wise, Stephen D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087642/
https://ncbi.nlm.nih.gov/pubmed/15855501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1813-1822.2005
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