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Combination of Candidate Microbicides Cellulose Acetate 1,2-Benzenedicarboxylate and UC781 Has Synergistic and Complementary Effects against Human Immunodeficiency Virus Type 1 Infection

The combination of two candidate microbicides, cellulose acetate 1,2-benzenedicarboxylate (CAP), a polymer that blocks human immunodeficiency virus type 1 (HIV-1) entry by targeting gp120 and gp41, and UC781, a tight-binding HIV-1 reverse transcriptase inhibitor (RTI), resulted in effective synergy...

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Hlavní autoři: Liu, Shuwen, Lu, Hong, Neurath, A. Robert, Jiang, Shibo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087640/
https://ncbi.nlm.nih.gov/pubmed/15855503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1830-1836.2005
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