Actinobacillus actinomycetemcomitans Toxin Induces Both Cell Cycle Arrest in the G(2)/M Phase and Apoptosis

We found that the culture supernatant of the periodontopathic bacterium Actinobacillus actinomycetemcomitans had a cytotoxic effect on several cell lines. In this study, we purified the toxin from the culture supernatant of A. actinomycetemcomitans Y4 by a four-step procedure: ammonium sulfate preci...

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Bibliographic Details
Main Authors: Ohguchi, Masahiro, Ishisaki, Akira, Okahashi, Nobuo, Koide, Masanori, Koseki, Takeyoshi, Yamato, Kenji, Noguchi, Toshihide, Nishihara, Tatsuji
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Molecular and Cellular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC108757/
https://ncbi.nlm.nih.gov/pubmed/9826381
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