Actinobacillus actinomycetemcomitans Toxin Induces Both Cell Cycle Arrest in the G(2)/M Phase and Apoptosis

We found that the culture supernatant of the periodontopathic bacterium Actinobacillus actinomycetemcomitans had a cytotoxic effect on several cell lines. In this study, we purified the toxin from the culture supernatant of A. actinomycetemcomitans Y4 by a four-step procedure: ammonium sulfate preci...

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Publié dans:	Infect Immun
Auteurs principaux:	Ohguchi, Masahiro, Ishisaki, Akira, Okahashi, Nobuo, Koide, Masanori, Koseki, Takeyoshi, Yamato, Kenji, Noguchi, Toshihide, Nishihara, Tatsuji
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Molecular and Cellular Pathogenesis
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108757/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826381/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.12.5980-5987.1998
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