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Production of the Potent Antibacterial Polyketide Erythromycin C in Escherichia coli
An Escherichia coli strain capable of producing the potent antibiotic erythromycin C (Ery C) was developed by expressing 17 new heterologous genes in a 6-deoxyerythronolide B (6dEB) producer strain. The megalomicin gene cluster was used as the source for the construction of two artificial operons th...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2005
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1087553/ https://ncbi.nlm.nih.gov/pubmed/15870344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.71.5.2539-2547.2005 |
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