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Neutrophil microtubules suppress polarity and enhance directional migration

How do microtubules, which maintain and direct polarity of many eukaryotic cells, regulate polarity of blood neutrophils? In sharp contrast to most cells, disrupting a neutrophil's microtubule network with nocodazole causes it to polarize and migrate [Niggli, V. (2003) J. Cell Sci. 116, 813–822...

詳細記述

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書誌詳細
主要な著者: Xu, Jingsong, Wang, Fei, Van Keymeulen, Alexandra, Rentel, Maike, Bourne, Henry R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087512/
https://ncbi.nlm.nih.gov/pubmed/15860582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502106102
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