Mode of Action of Invasion-Inhibitory Antibodies Directed against Apical Membrane Antigen 1 of Plasmodium falciparum

Antibodies against apical membrane antigen 1 (AMA-1) of Plasmodium falciparum inhibit merozoite invasion into erythrocytes. Invasion-inhibitory polyclonal AMA-1 antibodies inhibit secondary proteolytic processing and surface redistribution of AMA-1 on merozoites. We present evidence supporting inhib...

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Bibliographische Detailangaben
Hauptverfasser: Dutta, Sheetij, Haynes, J. David, Barbosa, Arnoldo, Ware, Lisa A., Snavely, Jeffrey D., Moch, J. Kathleen, Thomas, Alan W., Lanar, David E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087451/
https://ncbi.nlm.nih.gov/pubmed/15784553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.4.2116-2122.2005
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