Elucidation of the Monoclonal Antibody 5G8-Reactive, Virulence-Associated Lipopolysaccharide Epitope of Haemophilus influenzae and Its Role in Bacterial Resistance to Complement-Mediated Killing

The phase-variable locus lex2 is required for expression of a Haemophilus influenzae lipopolysaccharide (LPS) epitope of previously unknown structure. This epitope, which is reactive with monoclonal antibody (MAb) 5G8, has been associated with virulence of type b strains. When strain RM118 (from the...

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Detalhes bibliográficos
Main Authors: Griffin, Ruth, Cox, Andrew D., Makepeace, Katherine, Richards, James C., Moxon, E. Richard, Hood, Derek W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087420/
https://ncbi.nlm.nih.gov/pubmed/15784565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.4.2213-2221.2005
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