Role of Complement in Defense of the Middle Ear Revealed by Restoring the Virulence of Nontypeable Haemophilus influenzae siaB Mutants

Nontypeable (NT) Haemophilus influenzae is an important cause of otitis media in children. We have shown previously that NT H. influenzae mutants defective in their ability to sialylate lipopolysaccharide (LPS), called siaB mutants, show attenuated virulence in a chinchilla model of experimental oti...

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Detaylı Bibliyografya
Asıl Yazarlar: Figueira, Marisol A., Ram, Sanjay, Goldstein, Richard, Hood, Derek W., Moxon, E. Richard, Pelton, Stephen I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Bacterial Infections
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828410/
https://ncbi.nlm.nih.gov/pubmed/17088344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01054-06
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