The Purinergic P2X7 Receptor Is Not Required for Control of Pulmonary Mycobacterium tuberculosis Infection

The importance in vivo of P2X7 receptors in control of virulent Mycobacterium tuberculosis was examined in a low-dose aerosol infection mouse model. P2X7(−/−) mice controlled infection in lungs as well as wild-type mice, suggesting that the P2X7 receptor is not required for control of pulmonary M. t...

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Autors principals: Myers, Amy J., Eilertson, Brandon, Fulton, Scott A., Flynn, JoAnne L., Canaday, David H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087366/
https://ncbi.nlm.nih.gov/pubmed/15845532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.5.3192-3195.2005
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