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The Unique N-Terminus of R-Ras Is Required for Rac Activation and Precise Regulation of Cell Migration

The Ras family GTPase, R-Ras, elicits important integrin-dependent cellular behaviors such as adhesion, spreading and migration. While oncogenic Ras GTPases and R-Ras share extensive sequence homology, R-Ras induces a distinct set of cellular behaviors. To explore the structural basis for these diff...

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Bibliografiske detaljer
Main Authors: Holly, Stephen P., Larson, Mark K., Parise, Leslie V.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087249/
https://ncbi.nlm.nih.gov/pubmed/15772154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-12-0917
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