Effect of Clostridium difficile Toxin A on Human Colonic Lamina Propria Cells: Early Loss of Macrophages Followed by T-Cell Apoptosis

We have previously shown that Clostridium difficile toxin A induces detachment of human colonic epithelial cells from the basement membrane and subsequent cell death by apoptosis. Because these cells require adhesion-dependent signalling from the extracellular matrix for survival, their detachment f...

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Detalles Bibliográficos
Main Authors: Mahida, Y. R., Galvin, A., Makh, S., Hyde, S., Sanfilippo, L., Borriello, S. P., Sewell, H. F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
Assuntos:
Host Response and Inflammation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC108684/
https://ncbi.nlm.nih.gov/pubmed/9784558
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