Disruption of an Internal Membrane-Spanning Region in Shiga Toxin 1 Reduces Cytotoxicity
Shiga toxin type 1 (Stx1) belongs to the Shiga family of bipartite AB toxins that inactivate eukaryotic 60S ribosomes. The A subunit of Stxs are N-glycosidases that share structural and functional features in their catalytic center and in an internal hydrophobic region that shows strong transmembran...
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| Published in: | Infect Immun |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1998
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC108656/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9784530/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.66.11.5252-5259.1998 |
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