Activation of Rho GTPases by Escherichia coli Cytotoxic Necrotizing Factor 1 Increases Intestinal Permeability in Caco-2 Cells

The cytotoxic necrotizing factor 1 (CNF1) activates Rho GTPases by deamidation of glutamine-63 and thereby induces redistribution of the actin cytoskeleton and formation of stress fibers. Here, we have studied the effects of CNF1 on the transepithelial resistance of Caco-2 cells, a human intestinal...

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Main Authors: Gerhard, Ralf, Schmidt, Gudula, Hofmann, Fred, Aktories, Klaus
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Host Response and Inflammation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC108639/
https://ncbi.nlm.nih.gov/pubmed/9784513
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