Purification, Potency, and Efficacy of the Botulinum Neurotoxin Type A Binding Domain from Pichia pastoris as a Recombinant Vaccine Candidate

Recombinant botulinum neurotoxin serotype A binding domain [BoNT/A(H(c))], expressed in Pichia pastoris, was developed as a vaccine candidate for preventing botulinum neurotoxin type A (BoNT/A) intoxication. After fermentation and cell disruption, BoNT/A(H(c)) was purified by using a three-step chro...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Byrne, Michael P., Smith, Theresa J., Montgomery, Vicki A., Smith, Leonard A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1998
Pynciau:
Microbial Immunity and Vaccines
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC108595/
https://ncbi.nlm.nih.gov/pubmed/9746584
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